In contrast to synthetic chemicals, herbal formulations combine herbs in precise amounts to provide medicinal or cosmetic benefits with fewer adverse effects. Herbal creams are semisolid emulsions that fall into the oil-in-water (O/W) or water-in-oil (W/O) categories. They are used for a variety of applications, including skin care and mosquito repellent. Millions of people worldwide are impacted by mosquitoes, including species like Aedes and Culex, which are important carriers of diseases like dengue and malaria. Repellents, which might be synthetic or natural, are frequently used in effective mosquito control. Natural options like those using Neem, Tulsi and Lemongrass extracts, are being explored as safer, biodegradable alternatives to synthetic chemicals like DEET. Herbal mosquito repellent cream offer a promising solution to prevent mosquito bites and associated diseases, minimizing health risks compared to conventional repellents. The aim of the study was to develop an herbal mosquito repellent cream using Neem extract and essential oils from Clove, Tulsi, and Lemongrass. The plant profiles include Neem known for its antimicrobial and mosquito repellent properties. Lemongrass used for its insecticidal and antimicrobial benefits, Tulsi valued for its antibacterial and immunomodulatory effects and Clove recognized for its insecticidal properties. The extraction methods involved maceration for Neem and Clevenger apparatus for the Essential oils. The cream was prepared using a water-in-oil emulsion method with ingredients including Beeswax, liquid paraffin, and coconut oil in the oil phase and glycerin, borax and rose water in the aqueous phase. Three formulations (F1, F2, and F3) were tested, with F1 showing the best stability, no phase separation, and no irritancy, making it suitable for further use.